brain neurons

Dopamine Addiction: How Addicts Are at the Whim of Pleasure Chemicals

In pop-culture, dopamine is the media-hyped brain chemical responsible for your addiction to gambling, cake, sex, drugs, love and rock and roll. It seems straightforward: do something pleasurable, get that hit of feel-good dopamine. When it fades, do it again, then again. No wonder the phrase dopamine addiction exists. Are addicts really at the whim of pleasure chemicals?

In reality, the role of dopamine addiction in drug or alcohol abuse is more complicated. Let’s explore what dopamine addiction is, how it affects the brain, and, crucially, what you can do about it.

Dopamine isn’t a pleasure chemical

Naturally-occurring opioid peptides in the brain, like endorphins, are responsible for feelings of pleasure and elation. Not dopamine. Dopamine is a neurotransmitter – a chemical signal that ferries information from one neuron to another. It sounds simple, but each of us has countless dopamine-firing and dopamine-receiving neurons that form a vast, complex network.

This vast network of dopamine influences many different bodily functions. Lactation, movement, hormone regulation, and even how much attention you pay during your third team meeting today. The specific effects of dopamine depend on how much is released, where in the brain it comes from, where it’s going, what type of cell the receiving neuron is, what the binding receptors are, and what job each neuron involved is doing.

Dopamine in the mesolimbic pathway

When most people talk about dopamine addiction and pleasure, they’re referring to dopamine in the mesolimbic pathway. The mesolimbic pathway is a brain tract that connects the nucleus accumbens to the frontal lobes. Dopamine release increases in this area when we are just about to engage in something pleasurable like sex, listening to our favourite song, watching our sports team win, or take drugs.

Dopamine is like an alarm inside the mesolimbic pathway, sounding just before you do something pleasurable. It says, This is going to feel good. Remember it so you can do it again soon. It’s an incredibly useful survival mechanism because it reinforces behaviours essential to survival. Sex feels good so we make babies. Fatty, sugary foods taste good because early humans had a better chance at surviving winters if they ate more of it. Sadly, behaviours that reward us neurochemically are sometimes more harm than good in modern society.

Let’s dive a little deeper.

The more unexpected the pleasure, the more intoxicating the high

To understand the role of dopamine addiction in drug use, lets look at how it works when we eat chocolate cake.

You decide to visit a new cafe you’ve heard so much about. You sit and order chocolate cake. It arrives looking even better than you thought it would. That jolt of joy you felt? That’s the dopamine response firing to a better-than-expected pleasure.

The first bite is everything you hoped it would be and more. How do they make a cake so chocolatey!? You get another hit of dopamine from another positive prediction error the taste is better than you thought it would be. You eat the whole thing and leave feeling intensely satisfied.

Several days later, you’re thinking about that cake again. You’re craving those zaps of pleasure. You go back, and the experience is amazing almost as good as the first time you went. You decide to go every Saturday for chocolate cake.

A few weeks pass, and you notice you’re getting less and less pleasure from the chocolate cake. It hasn’t changed. You just dona’t enjoy it so much. Next week, you order carrot cake.

You guessed it. When something is unexpectedly better than we thought it would be, more dopamine is released. When something is disappointing or as we expected it would be, less dopamine is released. Science calls it prediction error the difference between what you expect, and what you get.

Cruelly, our brains never stop interpreting addictive drugs as unexpectedly pleasurable

The better-than-expected prediction error doesn’t diminish over time when we take drugs. We get an intense dopamine high no matter how frequently we use. Worse, the properties of addictive drugs ensure that even 100% awful experiences are still remembered as highly pleasurable. They artificially increase dopamine levels, forcing your brain to predict that your experience will be amazing next time.

This artificial drug-induced dopamine high is what compels you to use again and again.

Dopamine addiction isn’t addiction to the pleasure drugs give. It’s the anticipation of the pleasure drugs give. This distinction will come as no surprise to long-term addicts who feel compelled to seek out their next hit, despite reporting dwindling joy from the drug itself.

Dopamine linked with co-occurring disorders

A huge amount of research suggests that a genetic inability to absorb dopamine might predispose certain individuals with psychological problems to drug abuse. Results indicate that drug addiction has a clear biological basis, and should be treated no less seriously than any other mental illness.

Many patients who suffer from addiction are reported to have experienced underlying mental health issues like depression and anxiety as well. The National Bureau of Economic Research reports that people who have ever experienced mental illness consume about 69% of all alcohol, 84% of all cocaine, and 68% of all cigarettes. Dual diagnosis identifying and treating two or more medical disorders simultaneously is crucial for treating psychological disorders alongside drug or alcohol addiction.

Seek help at The Dawn Drug Rehabilitation Centre Thailand

The Dawn Medical Rehab and Wellness Centre offers holistic treatment plans for addiction personalised to the needs of every individual. We also provide integrated dual diagnosis treatment for co-occurring disorders like depression, anxiety, PTSD or schizophrenia.

Contact us to speak confidentially with one of our Advisors and get started on your journey to recovery.

76Shares